Serological effects of cypermethrin on the kidneys of rabbit (Oryctolagus cuniculus)

Authors

  • Habiba Shabbir Department of Zoology, GC University, Lahore-54000 Pakistan.
  • Dilawar Hussain Department of Zoology, Faculty of Science & Technology, University of Central Punjab, Lahore-54000 Pakistan.
  • Zahra Hussain Department of Zoology, Faculty of Science & Technology, University of Central Punjab, Lahore-54000 Pakistan.
  • Maham Rafiq Department of Zoology, Faculty of Science & Technology, University of Central Punjab, Lahore-54000 Pakistan. https://orcid.org/0009-0000-8235-7852
  • Khadeeja Akram Department of Zoology, Faculty of Science & Technology, University of Central Punjab, Lahore-54000 Pakistan https://orcid.org/0009-0001-8800-3374
  • Areeba Subtain Department of Zoology, Faculty of Science & Technology, University of Central Punjab, Lahore-54000 Pakistan. https://orcid.org/0009-0000-3053-7229
  • Shanza Nazar Department of Zoology, Faculty of Science & Technology, University of Central Punjab, Lahore-54000 Pakistan.
  • Mahnoor Raja Department of Zoology, Faculty of Science & Technology, University of Central Punjab, Lahore-54000 Pakistan

DOI:

https://doi.org/10.56946/jzs.v2i1.355

Keywords:

Cypermethrin, rabbit, urea, creatinine, serological

Abstract

Cypermethrin a commonly used synthetic pyrethroid insecticide, has become a big concern due to its harmful impact on animals. In this study, cypermethrin's (CY) serological effects were studied on the kidneys of rabbit (Oryctolagus cuniculus). Twenty rabbits were divided into four groups including three experimental (G2, G3 & G4) and one control group (G1). The three experimental groups were exposed to 500mg/kg (G2), 1000mg/kg (G3), and 1500mg/kg (G4) of dose of cypermethrin respectively, every day for fifteen days.  Blood sampling was done on the 5th, 10th, and 15th day of the experiment, the serum was separated from blood samples and two parameters including urea and creatinine were studied. The results indicated that both Urea and Creatine values were significantly different (p≤0.05) in all three experimental groups that were given cypermethrin treatment compared to the control group. In conclusion, cypermethrin is highly dangerous for mammals including rabbits when exposed to high doses.

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Published

2024-05-27
CITATION
DOI: 10.56946/jzs.v2i1.355

How to Cite

Shabbir, H., Hussain, D., Hussain, Z., Rafiq, M., Akram, K., Subtain, A., … Raja, M. (2024). Serological effects of cypermethrin on the kidneys of rabbit (Oryctolagus cuniculus) . Journal of Zoology and Systematics, 2(1), 1–9. https://doi.org/10.56946/jzs.v2i1.355

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